C Terminal Half Fragment (50 kDa) of Heavy Chain Components ofClostridium botulinumType C and D Neurotoxins Can Be Used as an Effective Vaccine
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چکیده
منابع مشابه
Vaccination with recombinant whole heavy chain fragments of Clostridium botulinum Type C and D neurotoxins.
Mice and ducks were subcutaneously immunized with recombinant whole heavy (H) chains of Clostridium botulinum type C and D neurotoxins, which were expressed as glutathione S-transferase fusion proteins. In the case of mice, it was confirmed that two immunizations with type C- and D-H chains, 10 microg each time, significantly increased the specific antibodies against 100-kDa H chains of type C ...
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ژورنال
عنوان ژورنال: Microbiology and Immunology
سال: 2007
ISSN: 0385-5600
DOI: 10.1111/j.1348-0421.2007.tb03919.x